A genetic disorder affecting the tissues connecting all the organs of the body, the Marfan syndrome affects people of all races and ethnic backgrounds. As per the statistical analysis, commonly prevalent in America, this syndrome affects at least 1 out of 5000 people in the country. Due to the abnormal chemical composition of this syndrome the strength of the connective tissue, which connects all the cells tissues and organs in a body, is weakened. The heart, blood vessels, cartilage, lungs, bones, nervous system, tendons, skin, eyes, and other vital organs of the body are adversely affected. Studies have shown that the Marfan syndrome severely damages the aorta by rupturing its inner layer that causes bleeding in the wall of the vessel further affecting the effective supply of blood to the other parts of the body. The other danger of Marfan syndrome is a mitral valve prolapse that causes breathlessness and rapid and irregular heart beat in the patient suffering from this disorder.
Effect of Marfan Syndrome on Pregnancy
Women suffering with Marfan syndrome are in much danger as this disorder enhances pressure on the heart and blood vessels. Though some women suffering with this disorder sail through the entire course of pregnancy but there are several factors associated which may turn hazardous for them including:
Women with Marfan syndrome require expert prenatal supervision, supervision during pregnancy and even after delivery and postnatal supervision. The patient suffering from this disorder needs at detailed counseling regarding the risk of transmission of the disease, possible alternatives to pregnancy, phenotypic variability, and the convenience of prenatal diagnostic to calculate risk factors.
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